Preparation method of optic nerve interface
The invention belongs to the field of biological nerves, and particularly discloses a preparation method of an optic nerve interface, a gradient stretching plate is introduced, a micron-sized metal wire is effectively prepared to ensure signal transmission, and a cooked silk fiber bundle obtained af...
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| creator | LIU BIN WANG JIEPING LUO XIYUE ZHOU CHAN LYU JINFENG ZHANG XUANJIE ZENG YAO |
| description | The invention belongs to the field of biological nerves, and particularly discloses a preparation method of an optic nerve interface, a gradient stretching plate is introduced, a micron-sized metal wire is effectively prepared to ensure signal transmission, and a cooked silk fiber bundle obtained after raw silk is degummed by an alkaline solution is used as silk fiber, so that the optic nerve interface is prepared. Meanwhile, the silk fibers are spirally wound on a template for multiple times and coated with polylactic acid with different concentrations in a layered mode for shaping and demolding, and the silk catheter is obtained, so that the prepared optic nerve interface not only can be effectively connected into optic nerves, but also can guarantee the stability and accuracy of electroneurographic signal characteristics; and the interference of the silk material on neural signal transmission is reduced.
本发明属于生物神经领域，具体公开一种视神经接口的制备方法，通过引入梯度拉伸板，有效制备了微米级金属导线以保证信号的传输，并将生丝经碱溶液脱胶过后所得到的熟丝纤维束作为所述蚕丝纤维，同时将所述蚕丝纤维在模板上 |
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本发明属于生物神经领域，具体公开一种视神经接口的制备方法，通过引入梯度拉伸板，有效制备了微米级金属导线以保证信号的传输，并将生丝经碱溶液脱胶过后所得到的熟丝纤维束作为所述蚕丝纤维，同时将所述蚕丝纤维在模板上</description><language>chi ; eng</language><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS ; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; FILTERS IMPLANTABLE INTO BLOOD VESSELS ; FIRST-AID KITS ; FOMENTATION ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES ; PROSTHESES ; TREATMENT OR PROTECTION OF EYES OR EARS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230428&DB=EPODOC&CC=CN&NR=116019606A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230428&DB=EPODOC&CC=CN&NR=116019606A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIU BIN</creatorcontrib><creatorcontrib>WANG JIEPING</creatorcontrib><creatorcontrib>LUO XIYUE</creatorcontrib><creatorcontrib>ZHOU CHAN</creatorcontrib><creatorcontrib>LYU JINFENG</creatorcontrib><creatorcontrib>ZHANG XUANJIE</creatorcontrib><creatorcontrib>ZENG YAO</creatorcontrib><title>Preparation method of optic nerve interface</title><description>The invention belongs to the field of biological nerves, and particularly discloses a preparation method of an optic nerve interface, a gradient stretching plate is introduced, a micron-sized metal wire is effectively prepared to ensure signal transmission, and a cooked silk fiber bundle obtained after raw silk is degummed by an alkaline solution is used as silk fiber, so that the optic nerve interface is prepared. Meanwhile, the silk fibers are spirally wound on a template for multiple times and coated with polylactic acid with different concentrations in a layered mode for shaping and demolding, and the silk catheter is obtained, so that the prepared optic nerve interface not only can be effectively connected into optic nerves, but also can guarantee the stability and accuracy of electroneurographic signal characteristics; and the interference of the silk material on neural signal transmission is reduced.
本发明属于生物神经领域，具体公开一种视神经接口的制备方法，通过引入梯度拉伸板，有效制备了微米级金属导线以保证信号的传输，并将生丝经碱溶液脱胶过后所得到的熟丝纤维束作为所述蚕丝纤维，同时将所述蚕丝纤维在模板上</description><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS</subject><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>FILTERS IMPLANTABLE INTO BLOOD VESSELS</subject><subject>FIRST-AID KITS</subject><subject>FOMENTATION</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><subject>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</subject><subject>PROSTHESES</subject><subject>TREATMENT OR PROTECTION OF EYES OR EARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAOKEotSCxKLMnMz1PITS3JyE9RyE9TyC8oyUxWyEstKktVyMwrSS1KS0xO5WFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFQCV5qSXxzn6GhmYGhpZmBmaOxsSoAQBtRyl5</recordid><startdate>20230428</startdate><enddate>20230428</enddate><creator>LIU BIN</creator><creator>WANG JIEPING</creator><creator>LUO XIYUE</creator><creator>ZHOU CHAN</creator><creator>LYU JINFENG</creator><creator>ZHANG XUANJIE</creator><creator>ZENG YAO</creator><scope>EVB</scope></search><sort><creationdate>20230428</creationdate><title>Preparation method of optic nerve interface</title><author>LIU BIN ; WANG JIEPING ; LUO XIYUE ; ZHOU CHAN ; LYU JINFENG ; ZHANG XUANJIE ; ZENG YAO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN116019606A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>BANDAGES, DRESSINGS OR ABSORBENT PADS</topic><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PROSTHESES</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><toplevel>online_resources</toplevel><creatorcontrib>LIU BIN</creatorcontrib><creatorcontrib>WANG JIEPING</creatorcontrib><creatorcontrib>LUO XIYUE</creatorcontrib><creatorcontrib>ZHOU CHAN</creatorcontrib><creatorcontrib>LYU JINFENG</creatorcontrib><creatorcontrib>ZHANG XUANJIE</creatorcontrib><creatorcontrib>ZENG YAO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIU BIN</au><au>WANG JIEPING</au><au>LUO XIYUE</au><au>ZHOU CHAN</au><au>LYU JINFENG</au><au>ZHANG XUANJIE</au><au>ZENG YAO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method of optic nerve interface</title><date>2023-04-28</date><risdate>2023</risdate><abstract>The invention belongs to the field of biological nerves, and particularly discloses a preparation method of an optic nerve interface, a gradient stretching plate is introduced, a micron-sized metal wire is effectively prepared to ensure signal transmission, and a cooked silk fiber bundle obtained after raw silk is degummed by an alkaline solution is used as silk fiber, so that the optic nerve interface is prepared. Meanwhile, the silk fibers are spirally wound on a template for multiple times and coated with polylactic acid with different concentrations in a layered mode for shaping and demolding, and the silk catheter is obtained, so that the prepared optic nerve interface not only can be effectively connected into optic nerves, but also can guarantee the stability and accuracy of electroneurographic signal characteristics; and the interference of the silk material on neural signal transmission is reduced.
本发明属于生物神经领域，具体公开一种视神经接口的制备方法，通过引入梯度拉伸板，有效制备了微米级金属导线以保证信号的传输，并将生丝经碱溶液脱胶过后所得到的熟丝纤维束作为所述蚕丝纤维，同时将所述蚕丝纤维在模板上</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES TREATMENT OR PROTECTION OF EYES OR EARS |
| title | Preparation method of optic nerve interface |
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