Modified gelatin

The present invention provides a modified gelatin comprising: (a) lysine residues; and (b) a lysine residue comprising a pendant side chain bearing a thiol group; wherein the modified gelatin comprises at least 50 [mu] mol/g of component (b) and at least 450 [mu] mol/g of components (a) and (b) in t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VAN BOXTEL HENDRIK ARIE, VAN DONGEN ELISABETH M. W. M
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention provides a modified gelatin comprising: (a) lysine residues; and (b) a lysine residue comprising a pendant side chain bearing a thiol group; wherein the modified gelatin comprises at least 50 [mu] mol/g of component (b) and at least 450 [mu] mol/g of components (a) and (b) in total. Also claimed are hydrogels, methods of making modified gelatin, and kits comprising modified gelatin and a cross-linking agent. 本发明提供了一种改性明胶,其包含:(a)赖氨酸残基;和(b)包含带有硫醇基团的悬垂侧链的赖氨酸残基;其中所述改性明胶包含至少50μmol/g组分(b)和总共至少450μmol/g组分(a)和(b)。本发明还要求保护水凝胶、制备改性明胶的方法、以及包括改性明胶和交联剂的试剂盒。