Detection method and kit for replicative adenovirus

The invention provides a method, a primer pair and a probe combination for quantitative detection of replicating adenovirus (RCA) in an adenovirus vector product, and a corresponding kit. The invention further provides a method and a kit for evaluating the quality of the adenovirus vector product, a...

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Bibliographische Detailangaben
Hauptverfasser: PAN XIANHUI, HAO YANZHE, LI XIU, NIU MIAO, SHI HUI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a method, a primer pair and a probe combination for quantitative detection of replicating adenovirus (RCA) in an adenovirus vector product, and a corresponding kit. The invention further provides a method and a kit for evaluating the quality of the adenovirus vector product, and the corresponding adenovirus vector product. 本发明提供了对腺病毒载体制品中复制型腺病毒(RCA)进行定量检测的方法、引物对和探针组合,及相应试剂盒。从而本发明还提供了用于评价腺病毒载体制品质量的方法和试剂盒,以及相应的腺病毒载体制品。