Fusion protein of hog cholera virus and application thereof

The invention discloses a fusion protein of hog cholera virus and application thereof, and belongs to the technical field of biology. The fusion protein of the hog cholera virus provided by the invention is obtained by connecting part of antigen epitopes of C protein, Erns protein and NS3 protein of...

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Hauptverfasser: MENG JIAYIN, LI LIYAN, XU YUNFANG, LIU GANG, LU XIAOYU, MO YAN, ZHENG JINLAI, CHEN GUOQING, PAN YIPING, DU HAOYUN, LI TIANZENG, XU YUANYUAN, ZHANG HUI, ZHAO BING, REN LISONG, LYU LUJIE, HAO JINBAO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a fusion protein of hog cholera virus and application thereof, and belongs to the technical field of biology. The fusion protein of the hog cholera virus provided by the invention is obtained by connecting part of antigen epitopes of C protein, Erns protein and NS3 protein of the hog cholera virus in series, and comprises or consists of an amino acid sequence as shown in SEQ ID NO: 5. The expression quantity of the fusion protein provided by the invention in a prokaryotic expression system is obviously improved, the positive detection rate of an antibody detection kit prepared from the fusion protein on a hog cholera virus antibody is obviously improved, a hog cholera virus E2 protein subunit vaccine immune antibody and a hog cholera virus wild virus infection antibody can be accurately identified and distinguished, and the purification of a pig farm is facilitated. 本发明公开一种猪瘟病毒的融合蛋白及其应用,属于生物技术领域。本发明提供的猪瘟病毒的融合蛋白为猪瘟病毒的C蛋白、Erns蛋白和NS3蛋白的部分抗原表位经串联得到,其包含SEQ ID NO:5所示的氨基酸序列或由其组成。本发明提供的融合蛋白在原核