Hybrid protein composition for inhibiting helicobacter pylori infection and application thereof

The invention provides a hybrid protein composition for inhibiting helicobacter pylori infection and application thereof, and relates to the technical field of medicines, the hybrid protein composition comprises AB469 hybrid antibacterial protein or an analogue thereof and lysozyme in a mass ratio o...

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Hauptverfasser: HUANG JINJIANG, LU WANYING, WU HONGYU, HUANG QINGSHAN, YE GUIZI, LI GUODONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a hybrid protein composition for inhibiting helicobacter pylori infection and application thereof, and relates to the technical field of medicines, the hybrid protein composition comprises AB469 hybrid antibacterial protein or an analogue thereof and lysozyme in a mass ratio of (50: 1)-(1: 100). The invention accidentally discovers that on the basis that the AB469 hybrid antibacterial protein or the analogue thereof has a remarkable inhibition effect on helicobacter pylori, the combination of the AB469 hybrid antibacterial protein or the analogue thereof and lysozyme in a mass ratio of (50: 1)-(1: 100) has a more remarkable synergistic effect, and a stronger helicobacter pylori inhibition effect can be provided. The hybrid protein composition can be used for preparing food, medicines or health care products for preventing or treating and inhibiting helicobacter pylori infection. 本发明提供了一种抑制幽门螺杆菌感染的杂合蛋白组合物及其应用,涉及药物技术领域,所述杂合蛋白组合物包括质量比为50:1-1:100的AB469杂合抗菌蛋白或其类似物与溶菌酶。本发明意外发现,在AB469杂合抗菌蛋白或其类