Method for screening IRES based on Levinstein distance and screened polynucleotide

The invention belongs to the technical field of bioinformatics and bioengineering, and particularly relates to a method for screening IRES based on the Levinstein distance, polynucleotide obtained through screening based on the method, a cyclic nucleic acid molecule containing the polynucleotide, a cyclization precursor nucleic acid molecule, a recombinant nucleic acid molecule, a recombinant expression vector, a recombinant host cell and application. According to the method, whether the IRES exists in the to-be-predicted sequence or not can be efficiently and accurately judged by comparing the mean values of the Levinstein distances between all the sample sequences and the to-be-predicted sequence, and the method has the advantages of being high in efficiency and accurate in screening result; the IRES screened by the IRES prediction method provided by the invention is high in activity, and abundant translation initiation elements are provided for application of the cyclic nucleic acid molecules in the aspect