Novel method for synthesizing para-substituted aniline compound

The invention belongs to the technical field of chemical synthesis, and relates to a preparation method for synthesizing para-substituted aniline compounds, in particular to a novel preparation method for synthesizing para-substituted aniline compounds 1 and 2, the method is mild in condition, simpl...

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Hauptverfasser: WEI BANGGUO, GUO JIAMING, MAO ZHUOYA, NIE XIAODI, SI CHANGMEI, LIN GUOQIANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of chemical synthesis, and relates to a preparation method for synthesizing para-substituted aniline compounds, in particular to a novel preparation method for synthesizing para-substituted aniline compounds 1 and 2, the method is mild in condition, simple to operate and good in yield, has excellent chemical selectivity and regioselectivity, and can be used for preparing the para-substituted aniline compounds 1 and 2. The used reagents are common reagents. According to the method, a series of para-substituted aniline compounds are efficiently synthesized with high regioselectivity, later modification can be carried out on active biomolecules, and a key way can be provided for construction of organic synthesis building blocks. Meanwhile, the method can conveniently realize laboratory gram-level preparation and is suitable for large-scale production. 本发明属化学合成技术领域,涉及合成对位取代苯胺类化合物的制备方法,具体涉及一种合成对位取代苯胺类化合物1和2的新的制备方法,所述方法条件温和,操作简单,收率良好,具有优秀的化学选择性和区域选择性,所用的试剂均为常用试剂。该方法高效、高区