Retinol ester derivative as well as preparation method and application thereof

The invention provides a retinol ester derivative and a preparation method and application thereof, and relates to the technical field of chemical synthesis.The preparation method comprises the step that retinol and carboxylic acid substances containing amino are subjected to a condensation reaction...

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Hauptverfasser: HU CHAOQUN, YUAN ZHIFA, YANG HE, YANG WEN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides a retinol ester derivative and a preparation method and application thereof, and relates to the technical field of chemical synthesis.The preparation method comprises the step that retinol and carboxylic acid substances containing amino are subjected to a condensation reaction, and the retinol ester derivative is obtained. The retinol ester derivative is different from existing mature retinol derivatives in the market, and the retinol ester derivative is a brand new compound formed by changing corresponding ester groups. According to the method, the technical problems that in the prior art, retinol cannot be well esterified, and the obtained retinol amino acid derivative is unstable are solved, and the technical effects that the reaction raw materials are low in price and easy to obtain, the process is efficient, pollution is avoided, and the atom economy is high are achieved. 本发明提供了一种视黄醇酯类衍生物及其制备方法、应用,涉及化学合成的技术领域,本发明的制备方法包括视黄醇与含有氨基的羧酸类物质发生缩合反应,得到视黄醇酯类衍生物,该视黄醇酯类衍生物与市面现有的成熟的视黄醇衍生物不同,该视黄醇