Substituted 5-hydroxyindole compounds as alpha-1 antitrypsin modulators

Novel compounds, compositions, and methods of use and preparation thereof, which are useful for the treatment of alpha-1 antitrypsin deficiency (AATD). 新颖化合物、组合物及其使用和制备方法，所述化合物和组合物可用于治疗α-1抗胰蛋白酶缺乏症(AATD)。

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Bibliographische Detailangaben
Hauptverfasser:	BOUCHER DAVID M, BANDARAGE UPUL K, SUH JUNGWON, FANNING LEV T. D, NUHANT PAUL M, MAXWELL JOHN P, TANG QIWEI, JOHNSON MICHAEL A. JR, BOYD MICHAEL J, DENG HONGLI, TAPLEY TIMOTHY L, CLARK MICHAEL P, KESAVAN SHIVKUMAR, FLEMING GARY S, HURLEY DENNIS J, WAHL NATHAN D, BRODNEY MICHAEL AARON, HALL ANDREW B, RONKIN STEVEN M, COTTRELL KEVIN MICHAEL, SWEET RAYMOND J, COLLIER PHILIP N, DAMARNIEZ VICTORIA, WANG JUN, JONES PAUL, MORRIS MARK A, THOMSON STEPHEN A, MERCESMITH DANIEL, GIROUX SIMON, DANIEL KEVIN B
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Novel compounds, compositions, and methods of use and preparation thereof, which are useful for the treatment of alpha-1 antitrypsin deficiency (AATD). 新颖化合物、组合物及其使用和制备方法，所述化合物和组合物可用于治疗α-1抗胰蛋白酶缺乏症(AATD)。