Stable topical formulations of 1 (r)-4-(5-(4-methoxy-3-propoxyphenyl) pyridin-3-yl)-1, 2-oxaborolan-2-ol

The present invention relates to chemically stable and physically stable topical formulations comprising (R)-4-(5-(4-methoxy-3-propoxyphenyl) pyridin-3-yl)-1, 2-oxaborolan-2-ol (PF-07038124) found to be used in the treatment of inflammatory disorders, and to methods of preparing said topical formula...

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1. Verfasser: YANG TERRIS Y
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to chemically stable and physically stable topical formulations comprising (R)-4-(5-(4-methoxy-3-propoxyphenyl) pyridin-3-yl)-1, 2-oxaborolan-2-ol (PF-07038124) found to be used in the treatment of inflammatory disorders, and to methods of preparing said topical formulations. 本发明涉及发现用于治疗炎性病症的包含(R)-4-(5-(4-甲氧基-3-丙氧基苯基)吡啶-3-基)-1,2-氧杂硼杂环戊烷-2-醇(PF-07038124)的化学稳定及物理稳定的局部制剂,以及涉及制备所述局部制剂的方法。