Gold nanorod antibody complex for detecting VEGFR2 (vascular endothelial growth factor receptor 2) protein expression in immunohistochemistry and preparation method of gold nanorod antibody complex

The invention provides a gold nanorod antibody complex for detecting VEGFR2 (vascular endothelial growth factor receptor 2) protein expression in immunohistochemistry and a preparation method of the gold nanorod antibody complex, relates to the field of in-vitro diagnosis, in particular to the field...

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1. Verfasser: FAN LINYANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a gold nanorod antibody complex for detecting VEGFR2 (vascular endothelial growth factor receptor 2) protein expression in immunohistochemistry and a preparation method of the gold nanorod antibody complex, relates to the field of in-vitro diagnosis, in particular to the field of immunohistochemistry diagnosis of cancer marker VEGFR2 expression, and particularly relates to a gold nanorod antibody complex for detecting VEGFR2 protein expression in immunohistochemistry and a preparation method of the gold nanorod antibody complex. According to the method, a VEGFR2 antibody and rod-shaped gold nanoparticles are connected together by adopting double-modified polyethylene glycol molecules, so that the detection performance of the original VEGFR2 antibody is enhanced, expression determination of VEGFR2 in a tissue slice is finally realized, and a standard is provided for screening of specific patients in precise targeted therapy of tumors. Compared with a traditional antibody immunohistochemi