Olmesartan medoxomil tablet and preparation method thereof

The invention provides an olmesartan medoxomil tablet. The olmesartan medoxomil tablet comprises olmesartan medoxomil, a filling agent, a disintegrating agent, an adhesive, vitamin C palmitate, linoleyl polyoxyethylene glyceride and a lubricant. Compared with the prior art, the stabilizer vitamin C palmitate is added into the prescription provided by the invention, so that the product stability is improved, the preparation process and the whole life cycle of product storage are ensured, and the quality is stable and controllable; the cosolvent linoleyl polyoxyethylene glyceride is added into the prescription, so that the solubility of the product is improved, the dissolution rate of the product is improved, and the bioavailability of the product is improved. 本发明提供了一种奥美沙坦酯片，包括奥美沙坦酯、填充剂、崩解剂、粘合剂、棕榈酸维生素C酯、亚油酰聚氧乙烯甘油酯与润滑剂。与现有技术相比，本发明提供的处方中加入稳定剂棕榈酸维生素C酯，提高产品稳定性，确保制剂过程及产品储存的整个生命周期，质量稳定可控；在处方中加入助溶剂亚油酰聚氧乙烯甘油酯，提高产品的溶解度，从而改善产品溶出速率，提高产品的生物利用度。