Pharmaceutical formulation

The present invention provides pharmaceutical formulations comprising a MALT1 inhibitor and a mixture comprising fatty acids and polyethylene glycol monoesters and polyethylene glycol diesters, and optionally fatty acids and monoglycerides, diglycerides, and triglycerides. Also described are solid d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HURME REINI, KIMPE KENNETH LEE, ZHU DONGHUA, SHAH SNEHAL M
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention provides pharmaceutical formulations comprising a MALT1 inhibitor and a mixture comprising fatty acids and polyethylene glycol monoesters and polyethylene glycol diesters, and optionally fatty acids and monoglycerides, diglycerides, and triglycerides. Also described are solid dosage forms comprising the pharmaceutical formulations, methods of making these and their use in methods of treatment. 本发明提供包含MALT1抑制剂和混合物的药物制剂,该混合物包含脂肪酸和聚乙二醇单酯和聚乙二醇二酯,以及任选的脂肪酸和甘油单酯、甘油二酯和甘油三酯。还描述了包含所述药物制剂的固体剂型、制备这些的方法以及它们在治疗方法中的用途。