Construction method and application of anti-glaucoma traditional Chinese medicine database

The invention provides a construction method and application of an anti-glaucoma traditional Chinese medicine database, and the construction method comprises the steps: obtaining a data set GSE27276 through a GEO database; converting a probe name in the data set GSE27276 into a gene name, determinin...

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Bibliographische Detailangaben
Hauptverfasser: LI LE, CAO JING, HUAN XIAOLONG, LI LI, TENG DAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a construction method and application of an anti-glaucoma traditional Chinese medicine database, and the construction method comprises the steps: obtaining a data set GSE27276 through a GEO database; converting a probe name in the data set GSE27276 into a gene name, determining an expression value of the same gene name and a corrected P value, screening to obtain a differential expression gene, and performing protein-protein interaction analysis and Cytoscape software analysis on the differential expression gene to obtain a core differential gene; capturing compounds in the TCMSP database and carrying out weight reduction treatment; and capturing corresponding traditional Chinese medicine names in the TCMSP database, carrying out weight reduction treatment, and constructing an anti-glaucoma traditional Chinese medicine database according to the traditional Chinese medicine names. According to the anti-glaucoma traditional Chinese medicine database query system designed based on the data