Anti-CD73 antibodies and uses thereof

The purpose of the present invention is to develop an antibody that is targeted to a CD73 antigen and has a higher function, and more specifically, an antibody for treating cancer that has higher activity. The present invention addresses the problem of finding an antibody or a human antibody derivative that includes a heavy chain/light chain complementarity determining region having a prescribed amino acid sequence, that binds to a CD73 antigen, and that activates T cells that are killing cancer cells. 本发明的目的在于，开发靶向CD73抗原的具有更高的功能的抗体、更具体而言具有更高的活性的癌症治疗用抗体。本发明示出：发现包含具有规定的氨基酸序列的重链/轻链的互补决定区、对CD73抗原具有结合性且激活对癌细胞具有杀伤性的T细胞的抗体或人抗体衍生物，能够解决上述课题。