Real-time fluorescent nucleic acid isothermal amplification detection kit for prostatic cancer and special primer and probe thereof
The invention discloses a real-time fluorescent nucleic acid isothermal amplification detection kit for prostatic cancer as well as a special primer and a probe thereof, and belongs to the technical field of tumor diagnosis. The kit provided by the invention comprises reagents for respectively and s...
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| creator | JU JINLIANG ZHANG SHIQI CUI ZHENLING RAN PENGZHAN |
| description | The invention discloses a real-time fluorescent nucleic acid isothermal amplification detection kit for prostatic cancer as well as a special primer and a probe thereof, and belongs to the technical field of tumor diagnosis. The kit provided by the invention comprises reagents for respectively and specifically detecting the following genes based on a real-time fluorescent nucleic acid isothermal amplification method: PCA3, ERG, DLX1, HOXC6, HOXC4, TDRD1, AMACR and MALAT1, and optional SPDEF and/or KLK3, the kit can be used for high-sensitivity detection of prostate cancer (including blood PSA grey region) by taking random urine of a patient as a sample to be detected, has an extremely high negative predictive value, and can be used for detection of prostate cancer (including blood PSA grey region). Therefore, unnecessary prostate needle biopsy of a negative object can be effectively avoided.
本发明公开一种前列腺癌的实时荧光核酸恒温扩增检测试剂盒及其专用引物和探针，属于肿瘤诊断技术领域。提供的试剂盒包括基于实时荧光核酸恒温扩增方法的分别特异性检测以下基因的试剂：PCA3、ERG、DLX1、HOXC6、HOXC4、TDRD1、A |
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本发明公开一种前列腺癌的实时荧光核酸恒温扩增检测试剂盒及其专用引物和探针，属于肿瘤诊断技术领域。提供的试剂盒包括基于实时荧光核酸恒温扩增方法的分别特异性检测以下基因的试剂：PCA3、ERG、DLX1、HOXC6、HOXC4、TDRD1、A</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230328&DB=EPODOC&CC=CN&NR=115851926A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230328&DB=EPODOC&CC=CN&NR=115851926A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JU JINLIANG</creatorcontrib><creatorcontrib>ZHANG SHIQI</creatorcontrib><creatorcontrib>CUI ZHENLING</creatorcontrib><creatorcontrib>RAN PENGZHAN</creatorcontrib><title>Real-time fluorescent nucleic acid isothermal amplification detection kit for prostatic cancer and special primer and probe thereof</title><description>The invention discloses a real-time fluorescent nucleic acid isothermal amplification detection kit for prostatic cancer as well as a special primer and a probe thereof, and belongs to the technical field of tumor diagnosis. The kit provided by the invention comprises reagents for respectively and specifically detecting the following genes based on a real-time fluorescent nucleic acid isothermal amplification method: PCA3, ERG, DLX1, HOXC6, HOXC4, TDRD1, AMACR and MALAT1, and optional SPDEF and/or KLK3, the kit can be used for high-sensitivity detection of prostate cancer (including blood PSA grey region) by taking random urine of a patient as a sample to be detected, has an extremely high negative predictive value, and can be used for detection of prostate cancer (including blood PSA grey region). Therefore, unnecessary prostate needle biopsy of a negative object can be effectively avoided.
本发明公开一种前列腺癌的实时荧光核酸恒温扩增检测试剂盒及其专用引物和探针，属于肿瘤诊断技术领域。提供的试剂盒包括基于实时荧光核酸恒温扩增方法的分别特异性检测以下基因的试剂：PCA3、ERG、DLX1、HOXC6、HOXC4、TDRD1、A</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNTjkOwjAQTEOBgD8sD6AIKAhKFIGoKBB9tGzGYoVjW7Z5AR_HHA-gmtHOsTOunmewXWQdQMY-fEQSuEzuIRYqxKI9afL5hjiwJR6CVaPCWb2jHhnyYXfNZHykEH3KRRQSdoJI7HpKAaIlHGJ58z0V3xX0boU302pk2CbMfjip5of9pT0uEHyHFLhMQu7aU103m6beLte71T-eF5TZSvo</recordid><startdate>20230328</startdate><enddate>20230328</enddate><creator>JU JINLIANG</creator><creator>ZHANG SHIQI</creator><creator>CUI ZHENLING</creator><creator>RAN PENGZHAN</creator><scope>EVB</scope></search><sort><creationdate>20230328</creationdate><title>Real-time fluorescent nucleic acid isothermal amplification detection kit for prostatic cancer and special primer and probe thereof</title><author>JU JINLIANG ; ZHANG SHIQI ; CUI ZHENLING ; RAN PENGZHAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115851926A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>JU JINLIANG</creatorcontrib><creatorcontrib>ZHANG SHIQI</creatorcontrib><creatorcontrib>CUI ZHENLING</creatorcontrib><creatorcontrib>RAN PENGZHAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JU JINLIANG</au><au>ZHANG SHIQI</au><au>CUI ZHENLING</au><au>RAN PENGZHAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Real-time fluorescent nucleic acid isothermal amplification detection kit for prostatic cancer and special primer and probe thereof</title><date>2023-03-28</date><risdate>2023</risdate><abstract>The invention discloses a real-time fluorescent nucleic acid isothermal amplification detection kit for prostatic cancer as well as a special primer and a probe thereof, and belongs to the technical field of tumor diagnosis. The kit provided by the invention comprises reagents for respectively and specifically detecting the following genes based on a real-time fluorescent nucleic acid isothermal amplification method: PCA3, ERG, DLX1, HOXC6, HOXC4, TDRD1, AMACR and MALAT1, and optional SPDEF and/or KLK3, the kit can be used for high-sensitivity detection of prostate cancer (including blood PSA grey region) by taking random urine of a patient as a sample to be detected, has an extremely high negative predictive value, and can be used for detection of prostate cancer (including blood PSA grey region). Therefore, unnecessary prostate needle biopsy of a negative object can be effectively avoided.
本发明公开一种前列腺癌的实时荧光核酸恒温扩增检测试剂盒及其专用引物和探针，属于肿瘤诊断技术领域。提供的试剂盒包括基于实时荧光核酸恒温扩增方法的分别特异性检测以下基因的试剂：PCA3、ERG、DLX1、HOXC6、HOXC4、TDRD1、A</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Real-time fluorescent nucleic acid isothermal amplification detection kit for prostatic cancer and special primer and probe thereof |
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