Hybrid antibiotic enzyme for killing animal-derived pathogenic bacteria and application of hybrid antibiotic enzyme

The invention relates to the technical field of antibiotic enzymes, in particular to a hybrid antibiotic enzyme for killing animal-derived pathogenic bacteria and application of the hybrid antibiotic enzyme. The hybrid antibiotic enzyme comprises a hybrid protein E1C1, and the hybrid protein E1C1 comprises a catalytic domain E1 as shown in SEQ ID NO: 2 and a binding domain C1 as shown in SEQ ID NO: 3. The invention also provides an application of the hybrid antibiotic enzyme in preparation of a pharmaceutical composition for controlling microbial infection, and a pharmaceutical composition with effective components comprising the hybrid antibiotic enzyme. The hybrid antibiotic enzyme disclosed by the invention can be used for rapidly cracking common animal-derived pathogenic bacteria such as escherichia coli, salmonella, staphylococcus aureus and helicobacter pylori, and also can be used for efficiently killing clinically separated common pathogenic bacteria such as acinetobacter baumannii, pseudomonas aerugi