Protease for gingival tissue of oral implant and preparation method thereof
The invention discloses protease for gingival tissue of an oral implant and a preparation method of the protease, and relates to the technical field of protease repair. The preservative is prepared from the following substances: 50 to 60 parts of matrix metalloproteinase mixed liquor, 15 to 20 parts...
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creator | CHU YUEFENG LIU GUOLIANG GOU HONGLIANG QI GUIBIN SUN JIANJIA CHI CHENGXI ZHANG SHIHAI ZHANG LE |
description | The invention discloses protease for gingival tissue of an oral implant and a preparation method of the protease, and relates to the technical field of protease repair. The preservative is prepared from the following substances: 50 to 60 parts of matrix metalloproteinase mixed liquor, 15 to 20 parts of serine protease mixed liquor, 10 to 15 parts of gingival protease K mixed liquor, 5 to 8 parts of pectinase, 5 to 8 parts of compound stabilizer and 1 to 3 parts of 0.025 mol/L calcium chloride solution. The compound protease adopting the matrix metalloproteinase, the serine protease and the gingival protease K as main components has a very good wound healing promotion effect on the wound surface of the gingival implant, can greatly relieve inflammation symptoms of gingival wounds and alveolar bone wounds, and has a very good application prospect.
本发明公开用于口腔种植体牙龈组织的蛋白酶及制备方法,涉及蛋白酶修复技术领域,按重量百分比计,由下述物质组成:基质金属蛋白酶混合液50-60份、丝氨酸蛋白酶混合液15-20份、牙龈蛋白酶K混合液10-15份、果胶酶5-8份、复合稳定剂5-8份和0.025mol/L氯化钙溶液1-3份。本发明采用基质金属蛋白酶、丝氨酸蛋白酶和牙龈蛋白酶 |
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本发明公开用于口腔种植体牙龈组织的蛋白酶及制备方法,涉及蛋白酶修复技术领域,按重量百分比计,由下述物质组成:基质金属蛋白酶混合液50-60份、丝氨酸蛋白酶混合液15-20份、牙龈蛋白酶K混合液10-15份、果胶酶5-8份、复合稳定剂5-8份和0.025mol/L氯化钙溶液1-3份。本发明采用基质金属蛋白酶、丝氨酸蛋白酶和牙龈蛋白酶</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230328&DB=EPODOC&CC=CN&NR=115845036A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230328&DB=EPODOC&CC=CN&NR=115845036A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHU YUEFENG</creatorcontrib><creatorcontrib>LIU GUOLIANG</creatorcontrib><creatorcontrib>GOU HONGLIANG</creatorcontrib><creatorcontrib>QI GUIBIN</creatorcontrib><creatorcontrib>SUN JIANJIA</creatorcontrib><creatorcontrib>CHI CHENGXI</creatorcontrib><creatorcontrib>ZHANG SHIHAI</creatorcontrib><creatorcontrib>ZHANG LE</creatorcontrib><title>Protease for gingival tissue of oral implant and preparation method thereof</title><description>The invention discloses protease for gingival tissue of an oral implant and a preparation method of the protease, and relates to the technical field of protease repair. The preservative is prepared from the following substances: 50 to 60 parts of matrix metalloproteinase mixed liquor, 15 to 20 parts of serine protease mixed liquor, 10 to 15 parts of gingival protease K mixed liquor, 5 to 8 parts of pectinase, 5 to 8 parts of compound stabilizer and 1 to 3 parts of 0.025 mol/L calcium chloride solution. The compound protease adopting the matrix metalloproteinase, the serine protease and the gingival protease K as main components has a very good wound healing promotion effect on the wound surface of the gingival implant, can greatly relieve inflammation symptoms of gingival wounds and alveolar bone wounds, and has a very good application prospect.
本发明公开用于口腔种植体牙龈组织的蛋白酶及制备方法,涉及蛋白酶修复技术领域,按重量百分比计,由下述物质组成:基质金属蛋白酶混合液50-60份、丝氨酸蛋白酶混合液15-20份、牙龈蛋白酶K混合液10-15份、果胶酶5-8份、复合稳定剂5-8份和0.025mol/L氯化钙溶液1-3份。本发明采用基质金属蛋白酶、丝氨酸蛋白酶和牙龈蛋白酶</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyjEKwkAQRuFtLES9w3gAwRAjthIUQRAL-zCYf5OFzc4yO3p-LTyA1eODN3fXu4qBC8iL0hDSEN4cyUIpL5B4Ev0yTDlyMuLUU1ZkVrYgiSbYKD3ZCIX4pZt5jgWrXxdufT492ssGWTqUzE8kWNfeqqo57JptvT_W_zwfdp81qg</recordid><startdate>20230328</startdate><enddate>20230328</enddate><creator>CHU YUEFENG</creator><creator>LIU GUOLIANG</creator><creator>GOU HONGLIANG</creator><creator>QI GUIBIN</creator><creator>SUN JIANJIA</creator><creator>CHI CHENGXI</creator><creator>ZHANG SHIHAI</creator><creator>ZHANG LE</creator><scope>EVB</scope></search><sort><creationdate>20230328</creationdate><title>Protease for gingival tissue of oral implant and preparation method thereof</title><author>CHU YUEFENG ; LIU GUOLIANG ; GOU HONGLIANG ; QI GUIBIN ; SUN JIANJIA ; CHI CHENGXI ; ZHANG SHIHAI ; ZHANG LE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115845036A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHU YUEFENG</creatorcontrib><creatorcontrib>LIU GUOLIANG</creatorcontrib><creatorcontrib>GOU HONGLIANG</creatorcontrib><creatorcontrib>QI GUIBIN</creatorcontrib><creatorcontrib>SUN JIANJIA</creatorcontrib><creatorcontrib>CHI CHENGXI</creatorcontrib><creatorcontrib>ZHANG SHIHAI</creatorcontrib><creatorcontrib>ZHANG LE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHU YUEFENG</au><au>LIU GUOLIANG</au><au>GOU HONGLIANG</au><au>QI GUIBIN</au><au>SUN JIANJIA</au><au>CHI CHENGXI</au><au>ZHANG SHIHAI</au><au>ZHANG LE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Protease for gingival tissue of oral implant and preparation method thereof</title><date>2023-03-28</date><risdate>2023</risdate><abstract>The invention discloses protease for gingival tissue of an oral implant and a preparation method of the protease, and relates to the technical field of protease repair. The preservative is prepared from the following substances: 50 to 60 parts of matrix metalloproteinase mixed liquor, 15 to 20 parts of serine protease mixed liquor, 10 to 15 parts of gingival protease K mixed liquor, 5 to 8 parts of pectinase, 5 to 8 parts of compound stabilizer and 1 to 3 parts of 0.025 mol/L calcium chloride solution. The compound protease adopting the matrix metalloproteinase, the serine protease and the gingival protease K as main components has a very good wound healing promotion effect on the wound surface of the gingival implant, can greatly relieve inflammation symptoms of gingival wounds and alveolar bone wounds, and has a very good application prospect.
本发明公开用于口腔种植体牙龈组织的蛋白酶及制备方法,涉及蛋白酶修复技术领域,按重量百分比计,由下述物质组成:基质金属蛋白酶混合液50-60份、丝氨酸蛋白酶混合液15-20份、牙龈蛋白酶K混合液10-15份、果胶酶5-8份、复合稳定剂5-8份和0.025mol/L氯化钙溶液1-3份。本发明采用基质金属蛋白酶、丝氨酸蛋白酶和牙龈蛋白酶</abstract><oa>free_for_read</oa></addata></record> |
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title | Protease for gingival tissue of oral implant and preparation method thereof |
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