Protease for gingival tissue of oral implant and preparation method thereof

The invention discloses protease for gingival tissue of an oral implant and a preparation method of the protease, and relates to the technical field of protease repair. The preservative is prepared from the following substances: 50 to 60 parts of matrix metalloproteinase mixed liquor, 15 to 20 parts...

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Bibliographische Detailangaben
Hauptverfasser: CHU YUEFENG, LIU GUOLIANG, GOU HONGLIANG, QI GUIBIN, SUN JIANJIA, CHI CHENGXI, ZHANG SHIHAI, ZHANG LE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses protease for gingival tissue of an oral implant and a preparation method of the protease, and relates to the technical field of protease repair. The preservative is prepared from the following substances: 50 to 60 parts of matrix metalloproteinase mixed liquor, 15 to 20 parts of serine protease mixed liquor, 10 to 15 parts of gingival protease K mixed liquor, 5 to 8 parts of pectinase, 5 to 8 parts of compound stabilizer and 1 to 3 parts of 0.025 mol/L calcium chloride solution. The compound protease adopting the matrix metalloproteinase, the serine protease and the gingival protease K as main components has a very good wound healing promotion effect on the wound surface of the gingival implant, can greatly relieve inflammation symptoms of gingival wounds and alveolar bone wounds, and has a very good application prospect. 本发明公开用于口腔种植体牙龈组织的蛋白酶及制备方法,涉及蛋白酶修复技术领域,按重量百分比计,由下述物质组成:基质金属蛋白酶混合液50-60份、丝氨酸蛋白酶混合液15-20份、牙龈蛋白酶K混合液10-15份、果胶酶5-8份、复合稳定剂5-8份和0.025mol/L氯化钙溶液1-3份。本发明采用基质金属蛋白酶、丝氨酸蛋白酶和牙龈蛋白酶