Construction method and application of rat cervical medullary hemorrhagic injury model

The invention discloses a method for constructing a rat cervical medullary hemorrhagic injury model, which is characterized in that collagenase is injected into the spinal cord of a rat to induce internal spinal cord hemorrhage so as to establish a spinal cord hemorrhagic injury model; compared with a traditional mode that mechanical injuries are caused to the back surface or a model is built through external acting force, the model building method provided by the invention does not cause tissue injuries to the rats, the component model method is simpler and more direct, the model is built on the premise that the physical health of the rats is guaranteed, and the influence of other diseases of the rats on the model is avoided. 本发明公开了一种大鼠颈髓出血性损伤模型的构建方法，其特征在于，通过对大鼠脊髓中注射胶原酶，诱导脊髓内出血，以此建立脊髓出血性损伤模型；与传统的对背表面造成机械损伤或通过外作用力来构建模型的方式相比，本发明提供的模型构建方法不会对大鼠造成组织损伤，且构件模型方法更简单直接，在保证大鼠体质健康的前提下构建模型，避免大鼠其他病症对该模型造成影响。