PDRN-containing nano-emulsion and preparation method thereof

The invention relates to a PDRN-containing nano-emulsion and a preparation method thereof, and belongs to the technical field of biology, the nano-emulsion comprises PDRN, an emulsifier, a co-emulsifier, an oil phase component and water, preferably Tween 80, Span 80, isopropyl myristate and purified water; the preparation method comprises the following steps: uniformly stirring and mixing PDRN and purified water to obtain a water-phase solution; heating and uniformly mixing the co-emulsifier and the oil-phase component, cooling to a certain temperature, adding the emulsifier, stirring and uniformly mixing to obtain an oil-phase solution; slowly adding the water-phase solution into the oil-phase solution to form the nano-emulsion. The nano-emulsion disclosed by the invention is small in particle size, has good stability and transdermal property, is helpful for drugs to enter cuticle, can also enter skin through hair follicles, and is beneficial to skin absorption. The preparation method of the nano-emulsion is