Lysophosphatidylcholine acyltransferase, nucleic acid molecule and application thereof

The invention discloses lysophosphatidylcholine acyltransferase, a nucleic acid molecule and application of the lysophosphatidylcholine acyltransferase, and belongs to the technical field of microbial synthetic biology or metabolic engineering. According to the invention, lysophosphatidylcholine acyltransferase (PtLPCAT) from phaeodactylum tricornutum is successfully applied, through overexpression in recombinant cells, the transfer efficiency of fatty acyl between a PC library and a CoA library can be greatly improved, substrate sources for synthesis of long-chain polyunsaturated fatty acids are increased, and the yield of the long-chain polyunsaturated fatty acids is increased. The relative content of the long-chain polyunsaturated fatty acid in the recombinant yarrowia lipolytica is effectively improved. According to the lysophosphatidylcholine acyltransferase provided by the invention, the loss of intermediate metabolites can be reduced, and the relative content of long-chain polyunsaturated fatty acids,