Nucleoside derivative for treating cancer and application thereof

The invention discloses a nucleoside compound with a novel structure, a salt thereof and a preparation method of the nucleoside compound. The nucleoside compound and the salt thereof show a relatively strong effect of inhibiting tumor proliferation in vivo, and do not show obvious side effects. Mean...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: FU HAIJIAN, HOU WEN, LI HAIDE
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention discloses a nucleoside compound with a novel structure, a salt thereof and a preparation method of the nucleoside compound. The nucleoside compound and the salt thereof show a relatively strong effect of inhibiting tumor proliferation in vivo, and do not show obvious side effects. Meanwhile, the compound disclosed by the invention does not have obvious stomach stimulation effect and renal toxicity, and shows a relatively good medical application prospect in cancer treatment. 本发明公开了一种具有新颖结构的核苷类化合物及其盐和其制备方法。所述的核苷类化合物及其盐在体内表现出较强的抑制肿瘤增殖的作用,并且没有表现出明显的副作用。同时,本发明的化合物没有明显的胃部刺激作用与肾毒性,在对癌症的治疗中显示出较好的医药应用前景。