Seven lignan compounds in radix zanthoxyli as well as extraction method and application of seven lignan compounds

The invention belongs to the technical field of medicine extraction, and provides seven lignan compounds in radix zanthoxyli as well as an extraction method and application of the seven lignan compounds. The compounds are compounds as shown in formulas 1-7. The preparation method comprises the follo...

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Hauptverfasser: LI MEISHAN, WANG CAIYI, QIN FENG, ZHOU MEIMEI, WANG FANFAN, LI JINJUN, JIANG JINGCHEN, WANG HENGSHAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of medicine extraction, and provides seven lignan compounds in radix zanthoxyli as well as an extraction method and application of the seven lignan compounds. The compounds are compounds as shown in formulas 1-7. The preparation method comprises the following steps: extracting by adopting an organic solvent to obtain the shinyleaf pricklyash root extract; dissolving the zanthoxylum nitidum extract in a tartaric acid solution with the mass fraction of 3%, filtering, and extracting filtrate with ethyl acetate; and combining the ethyl acetate extract and the acid water insoluble substance, sequentially extracting with petroleum ether, ethyl acetate and n-butyl alcohol, and concentrating to obtain the petroleum ether part, the ethyl acetate part and the n-butyl alcohol part. Performing silica gel column chromatography on the purified ethyl acetate part, performing gradient elution by using an eluent consisting of dichloromethane and methanol, analyzing and detecting fr