Synthesis method of spirotetramat

The invention provides a synthesis method of spirotetramat, and relates to the technical field of pesticide chemical industry. The preparation method comprises the following steps: mixing an SN-1 intermediate, ethyl chloroformate, an inorganic acid-binding agent, an amine catalyst and an organic sol...

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Hauptverfasser: CHENG FANGUI, ZHU ZONGRONG, CHEN MAO, LI HUIHU, YIN WANGHUA
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides a synthesis method of spirotetramat, and relates to the technical field of pesticide chemical industry. The preparation method comprises the following steps: mixing an SN-1 intermediate, ethyl chloroformate, an inorganic acid-binding agent, an amine catalyst and an organic solvent, and carrying out condensation reaction to obtain spirotetramat; the inorganic acid-binding agent comprises at least one of carbonate, bicarbonate and hydroxide. According to the method, at least one of carbonate, bicarbonate and hydroxide is used as the inorganic acid-binding agent, the inorganic acid-binding agent is free of pungent smell, low in cost and capable of being dissolved in water, no organic alkali waste water is generated in the spirotetramat synthesis process, the organic waste water treatment cost is greatly reduced, no nitrogen-containing waste gas is generated in the follow-up purification process, and the method is environmentally friendly. And the synthesis method is environment-friendly. M