Synthesis method of 2-aryl-3, 4-dihydro-1 (2H)-naphthalenone compound

The invention discloses a synthesis method of a 2-aryl-3, 4-dihydro-1 (2H)-naphthalenone compound, which comprises the following specific operations: under the protection of inert gas, in an aprotic solvent, mixing aryl formyl pyrrole, aryl ethylene, alkali and an additive according to a molar ratio of 1: 2: 2: 4 for reaction, then adding water for quenching, filtering, washing, and drying by distillation under reduced pressure to obtain the 2-aryl-3, 4-dihydro-1 (2H)-naphthalenone compound. And carrying out column chromatography separation to obtain the 2-aryl-3, 4-dihydro-1 (2H)-naphthalenone compound. The reaction is carried out under the condition of no metal catalysis, the raw materials are simple and easy to obtain, complex treatment is not needed, the substrate universality is good, and the synthesis steps are simple to operate. 本发明公开了一种2-芳基-3,4-二氢-1(2H)-萘酮类化合物的合成方法,具体操作如下：在惰性气体保护下，非质子溶剂中，将芳甲酰吡咯、芳基乙烯、碱和添加剂以摩尔比1:2:2:4混合进行反应，然后加入水淬灭，滤过，洗涤后减压蒸干，柱层析分离得到2-芳基-3,4-二氢-1(2H)-萘酮类化合物。本发明在无金属催化的条件下发生反应，原料简单易得，不需要经