Mycobacterium tuberculosis ethambutol drug resistance diagnostic marker and application thereof

The invention relates to the technical field of drug resistance of mycobacterium tuberculosis, and discloses a diagnostic marker for ethambutol drug resistance of mycobacterium tuberculosis and application of the diagnostic marker. The diagnostic marker for the ethambutol resistance of the mycobacterium tuberculosis comprises at least one of coE, lgt, pip, prpD, nirB, ponA1 and vapC15. The diagnostic marker can be used for detecting whether the mycobacterium tuberculosis is resistant to ethambutol, so that the detection process is simpler, quicker and more accurate, and the cost is lower. 本发明涉及结核分枝杆菌耐药性的技术领域，公开了一种结核分枝杆菌乙胺丁醇耐药性诊断标志物及应用。该结核分枝杆菌乙胺丁醇耐药性诊断标志物包括coaE、lgt、pip、prpD、nirB、ponA1、vapC15中至少一种。使用该诊断标志物可检测结核分枝杆菌对乙胺丁醇是否耐药，使检测过程更简单、更快速、更准确以及成本更低。