Polypeptide with self-assembly and adhesion performance and application thereof

The invention discloses a polypeptide with self-assembly and adhesion performance and application of the polypeptide. The polypeptide is derived from lactobacillus acidophilus CICC 6074, and the amino acid sequence of the polypeptide is shown as ATTINASSAINTNTNAKYDVDVT. The invention further discloses a preparation method of the polypeptide with the self-assembly and adhesion performance and application of the polypeptide with the self-assembly and adhesion performance. The polypeptide disclosed by the invention can be self-assembled on the polar liposome, so that the stability of the polar liposome is kept; the emulsion liposome modified by the polypeptide can be adhered to the surface of HT-29 cells, and can be used for improving the intestinal adhesion of the emulsion liposome and promoting the high efficiency of drug absorption. Researches show that the polypeptide can be used as a transfer material of nano-drugs, can be used in the fields of food, drugs and the like, and has a very good market prospect.