Radiomarker of albumin indocyanine green compound as well as preparation method and application of radiomarker

The invention provides a radiomarker of an albumin indocyanine green compound and a preparation method and application of the radiomarker, and the preparation method comprises the following steps: adding human serum albumin and indocyanine green into water, inducing the human serum albumin to be self-assembled by the indocyanine green to form nanoparticles, and dialyzing to obtain the albumin indocyanine green compound; and performing radioisotope labeling on the albumin indocyanine green compound to obtain the radiomarker of the albumin indocyanine green compound. The preparation method of the radiation marker of the albumin indocyanine green compound is high in operation safety, the particle size of the obtained radiation marker is controllable, and the radiation marker can be used for sentinel lymph node imaging and treatment. 本发明提供一种白蛋白吲哚菁绿复合物的放射标记物及其制备方法和应用，包括：将人血清白蛋白和吲哚菁绿加入水中，吲哚菁绿诱导人血清白蛋白自组装形成纳米颗粒，透析，得到白蛋白吲哚菁绿复合物；对白蛋白吲哚菁绿复合物进行放射性同位素标记，得到白蛋白吲哚菁绿复合物的放射标记物。本发明白蛋白吲哚菁绿复合物的放射标记物的制备方法操作安全性高、所得放射标记物的粒径可控，可用于前哨淋