Anti-osteoporosis composition containing pinoresinol diglucoside and application thereof

The invention provides an anti-osteoporosis composition containing pinoresinol diglucoside and application of the anti-osteoporosis composition. The composition is prepared from the following components: pinoresinol diglucoside, pinoresinol monoglucoside and pinoresinol. The mass ratio of the pinoresinol diglucoside to the pinoresinol monoglucoside to the pinoresinol is 1: (0.2 to 0.4): (0.05 to 0.25). The composition provided by the invention is stable in quality, high in safety, suitable for being taken for a long time and good in osteoporosis treatment effect, can be used for senile osteoporosis, and has a more remarkable effect of inhibiting reduction of bone mineral density in an ovarian castration female rat osteoporosis model. 本发明提供了一种抗骨质疏松的含松脂醇二葡萄糖苷的组合物及其应用，所述组合物由松脂醇二葡萄糖苷、松脂醇单葡萄糖苷、松脂醇组分组成；所述松脂醇二葡萄糖苷、松脂醇单葡萄糖苷、松脂醇的质量比为1∶0.2-0.4∶0.05-0.25。本发明提供的组合物质量稳定、安全性高，适合长期服用，治疗骨质疏松症的效果好，该组合物可用于老年性骨质疏松症，在卵巢去势雌性大鼠骨质疏松模型中，具有更显著的抑制骨密度降低的作用。