Umbilical cord mesenchymal stem cell, umbilical cord mesenchymal stem cell preparation and application thereof

The invention provides umbilical cord mesenchymal stem cells. A preparation method of the umbilical cord mesenchymal stem cells comprises the following steps: separating Wharton's jelly, dividing the Wharton's jelly into tissue blocks, culturing with a first culture medium, performing dige...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	LIU QING, CHEN TENGFEI, CHEN YI, LI WENQIANG, WU ZHONGQI, YANG YONGFENG, SU XI, CAO JIANFU, ZHANG LUWEN, CUI XIANGZHENG, WU LEIZHEN, KANG NING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention provides umbilical cord mesenchymal stem cells. A preparation method of the umbilical cord mesenchymal stem cells comprises the following steps: separating Wharton's jelly, dividing the Wharton's jelly into tissue blocks, culturing with a first culture medium, performing digestion treatment, culturing with a second culture medium and performing cryopreservation with a cryopreservation solution. In addition, the invention further provides an umbilical cord mesenchymal stem cell preparation and application of the umbilical cord mesenchymal stem cell preparation in preparation of drugs for treating schizophrenia, schizophrenia diagnosis and curative effect evaluation of the schizophrenia drugs. Firstly, the umbilical cord mesenchymal stem cells enable schizophrenia newborn rats to recover to normal activity, and have a curative effect on cognitive impairment of schizophrenia; secondly, the relative content of three mRNAs (messenger ribonucleic acid), namely beta-NGF, D2 and Iba1 in schizophrenia ch