Preparation method of difenoconazole

The invention relates to the technical field of bactericides, and particularly discloses a preparation method of difenoconazole. The invention relates to a preparation method of difenoconazole, which comprises the following steps: sequentially carrying out bromination reaction, cyclization reaction and condensation reaction on 2-chloro-4-(4-chlorophenoxy) acetophenone to obtain a difenoconazole crude product; and purifying the crude product of difenoconazole to obtain a finished product of difenoconazole. The synthetic route is represented by a reaction equation. The production process of difenoconazole, provided by the invention, is relatively high in bromine utilization rate, and can effectively improve economic benefits and environmental benefits of difenoconazole production. 本申请涉及杀菌剂技术领域，具体公开了一种苯醚甲环唑的制备方法。一种苯醚甲环唑的制备方法，包括以下步骤：2-氯-4-（4-氯苯氧基）苯乙酮依次经溴化反应、环化反应、缩合反应，得到苯醚甲环唑粗品；苯醚甲环唑粗品再经纯化后得到成品苯醚甲环唑；合成路线用反应方程式表示如下：。本申请所提供的苯醚甲环唑的生产工艺溴素利用率较高，可以有效改善生产苯醚甲环唑的经济效益和环境效益。