1, 1-dioxo-1, 2-benzisothiazole-3 (2H)-one sodium salt crystallization process

The invention belongs to the technical field of food additive crystallization. The invention discloses a novel crystallization process of 1, 1-dioxo-1, 2-benzisothiazole-3 (2H)-one sodium salt, and relates to the technical field of sodium salt crystallization. The method comprises the following step...

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Hauptverfasser: WEI CHENG, JI KYUNGOL, CHI JIAN, ZHAI JIANGCHAO, LIU MIMIN, LIU MILE, ZHANG YAZHOU, LI WEI, LIU HUI, ZHAO XIN, HAN YUAN, XU QINGBANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of food additive crystallization. The invention discloses a novel crystallization process of 1, 1-dioxo-1, 2-benzisothiazole-3 (2H)-one sodium salt, and relates to the technical field of sodium salt crystallization. The method comprises the following steps: firstly, carrying out impurity removal and filtration by using activated carbon, adding a nucleating agent into a solution after filtration, and carrying out cooling crystallization and filtration in a stirring state to obtain 1, 1-dioxo-1, 2-benzisothiazole-3 (2H)-one sodium salt; the preparation method comprises the following steps: firstly, adding an alkali into a filtrate, removing ammonia gas in the filtrate, removing impurities by using activated carbon, filtering, then adding water, 2-methoxycarbonyl benzene sulfonamide and sodium carbonate or sodium bicarbonate into the filtered filtrate, reacting, and carrying out circular treatment on the obtained aqueous solution of 1, 1-dioxo-1, 2-benzisothiazole-3 (