Ophthalmic mecobalamine preparation and application thereof

The invention provides a mecobalamine ophthalmic preparation as well as a preparation method and application thereof, and belongs to the technical field of eye drops. The mecobalamin ophthalmic preparation provided by the invention comprises the following components: a mecobalamin active compound and procyanidine, wherein the mass ratio of the mecobalamin active compound to the procyanidine is (0.02-0.1): (0-0.5); the dosage form of the mecobalamine ophthalmic preparation is one or more of a drop, a hydrogel preparation and a liposome preparation. The mecobalamin is used as an active component, the procyanidine is used as a synergist of the mecobalamin, and the obtained mecobalamin ophthalmic preparation can promote corneal nerve regeneration, promote corneal epithelium healing, effectively inhibit corneal neovascularization and improve corneal perception. According to the mecobalamine ophthalmic preparation provided by the invention, complications caused by long-term systemic application of mecobalamine are