Application of high molecular weight oat beta-glucan extract

The invention discloses a high-molecular-weight oat beta-glucan extract which is characterized in that the content of beta-glucan with the relative molecular mass larger than or equal to 300 kDa is larger than or equal to 95%, and the high-molecular-weight oat beta-glucan extract has the effect of r...

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Bibliographische Detailangaben
Hauptverfasser: ZHANG ZHENHUI, LI BING, WU HONG, LI LIN, CAI JIAXIAN, WU YI, ZHANG XIA, WU YONGTAI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a high-molecular-weight oat beta-glucan extract which is characterized in that the content of beta-glucan with the relative molecular mass larger than or equal to 300 kDa is larger than or equal to 95%, and the high-molecular-weight oat beta-glucan extract has the effect of relieving abnormal glycolipid metabolism induced by food-borne advanced glycation end products. The high molecular weight oat beta-glucan extract is obtained by pretreatment, extraction, concentration, separation, adsorption, nanofiltration, drying and determination. The weight and blood sugar of a food-borne advanced glycation end product induced model animal can be obviously reduced by 19-25% and 8-21%, the oral glucose tolerance impairment of the model animal can be obviously relieved by 9-17%, and the insulin resistance can be obviously inhibited; and fat accumulation in abdominal adipose tissue, perirenal adipose tissue, epididymal adipose tissue and mesenteric adipose tissue of a model animal is remarkably inh