Epirubicin compound preparation as well as preparation method and application thereof

The invention discloses an epirubicin compound preparation which comprises epirubicin or a soluble salt thereof, imiquimod or a soluble salt thereof, a pH regulator and a freeze-drying protective additive. The compound preparation disclosed by the invention is beneficial to protecting the long-term stability of epirubicin or soluble salt thereof in a mixture, and meanwhile, the mixed preparation has a better tumor inhibition effect in bladder perfusion tumor treatment and can cause stronger anti-tumor immune response. 本发明公开了一种表柔比星复方制剂，包括表柔比星或其可溶性盐，咪喹莫特或其可溶性盐，pH调节剂，以及冻干保护剂。本发明的复方制剂有助于保护表柔比星或其可溶性盐在混合物中的长期稳定性，同时，混合制剂在膀胱灌注肿瘤治疗中，具有较好的肿瘤抑制效果，能够引起更强烈的抗肿瘤免疫反应。