Swine influenza A virus vaccine comprising two different RNA replicon particles
The present invention relates to an immunogenic composition comprising first and second RNA replicon particles. The first RNA replicon particle comprises a nucleic acid construct comprising first and second nucleic acid sequences encoding first and second hemagglutinin (HA) antigens of swine influen...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | MOGLER MATTHEW A NAGARAJ, BHARATH, H |
| description | The present invention relates to an immunogenic composition comprising first and second RNA replicon particles. The first RNA replicon particle comprises a nucleic acid construct comprising first and second nucleic acid sequences encoding first and second hemagglutinin (HA) antigens of swine influenza A virus (IAV-S). In some embodiments, the first HA antigen is an HA antigen of the A/swing/Gent/1/1984-like H3N2 (Gent/84) lineage, and the second HA antigen is an HA antigen of the A (H1N1) pdm09 (pdm09) lineage. The second RNA replicon particle comprises a nucleic acid construct comprising third and fourth nucleic acid sequences encoding third and fourth HA antigens of IAV-S. The third HA antigen is the HA antigen of the A/swing/Scotland/410440/1994-like H1huN2 (Scot/94) lineage, and the fourth HA antigen is the HA antigen of the Eurasian avian-like H1avN1 (EA) lineage. In other embodiments, the present invention relates to vaccines useful against influenza A virus infection and comprising an immunogenic compo |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN115697398A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN115697398A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN115697398A3</originalsourceid><addsrcrecordid>eNqNyk0KwjAQQOFsXIh6h_EALkrxp8tQFFcV1H0ZxokMxElI0hY8vQgewNVbfG9uLrdJlEHU-YH1jWBhlDRkGJHoKxReMUkWfUKZAjzEOU6sBa6dhcTRCwWFiKkIec5LM3PoM69-XZj16XhvzxuOoecckVi59G1XVdtds6-bg63_eT5WzzcN</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Swine influenza A virus vaccine comprising two different RNA replicon particles</title><source>esp@cenet</source><creator>MOGLER MATTHEW A ; NAGARAJ, BHARATH, H</creator><creatorcontrib>MOGLER MATTHEW A ; NAGARAJ, BHARATH, H</creatorcontrib><description>The present invention relates to an immunogenic composition comprising first and second RNA replicon particles. The first RNA replicon particle comprises a nucleic acid construct comprising first and second nucleic acid sequences encoding first and second hemagglutinin (HA) antigens of swine influenza A virus (IAV-S). In some embodiments, the first HA antigen is an HA antigen of the A/swing/Gent/1/1984-like H3N2 (Gent/84) lineage, and the second HA antigen is an HA antigen of the A (H1N1) pdm09 (pdm09) lineage. The second RNA replicon particle comprises a nucleic acid construct comprising third and fourth nucleic acid sequences encoding third and fourth HA antigens of IAV-S. The third HA antigen is the HA antigen of the A/swing/Scotland/410440/1994-like H1huN2 (Scot/94) lineage, and the fourth HA antigen is the HA antigen of the Eurasian avian-like H1avN1 (EA) lineage. In other embodiments, the present invention relates to vaccines useful against influenza A virus infection and comprising an immunogenic compo</description><language>chi ; eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230203&DB=EPODOC&CC=CN&NR=115697398A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230203&DB=EPODOC&CC=CN&NR=115697398A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MOGLER MATTHEW A</creatorcontrib><creatorcontrib>NAGARAJ, BHARATH, H</creatorcontrib><title>Swine influenza A virus vaccine comprising two different RNA replicon particles</title><description>The present invention relates to an immunogenic composition comprising first and second RNA replicon particles. The first RNA replicon particle comprises a nucleic acid construct comprising first and second nucleic acid sequences encoding first and second hemagglutinin (HA) antigens of swine influenza A virus (IAV-S). In some embodiments, the first HA antigen is an HA antigen of the A/swing/Gent/1/1984-like H3N2 (Gent/84) lineage, and the second HA antigen is an HA antigen of the A (H1N1) pdm09 (pdm09) lineage. The second RNA replicon particle comprises a nucleic acid construct comprising third and fourth nucleic acid sequences encoding third and fourth HA antigens of IAV-S. The third HA antigen is the HA antigen of the A/swing/Scotland/410440/1994-like H1huN2 (Scot/94) lineage, and the fourth HA antigen is the HA antigen of the Eurasian avian-like H1avN1 (EA) lineage. In other embodiments, the present invention relates to vaccines useful against influenza A virus infection and comprising an immunogenic compo</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyk0KwjAQQOFsXIh6h_EALkrxp8tQFFcV1H0ZxokMxElI0hY8vQgewNVbfG9uLrdJlEHU-YH1jWBhlDRkGJHoKxReMUkWfUKZAjzEOU6sBa6dhcTRCwWFiKkIec5LM3PoM69-XZj16XhvzxuOoecckVi59G1XVdtds6-bg63_eT5WzzcN</recordid><startdate>20230203</startdate><enddate>20230203</enddate><creator>MOGLER MATTHEW A</creator><creator>NAGARAJ, BHARATH, H</creator><scope>EVB</scope></search><sort><creationdate>20230203</creationdate><title>Swine influenza A virus vaccine comprising two different RNA replicon particles</title><author>MOGLER MATTHEW A ; NAGARAJ, BHARATH, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115697398A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MOGLER MATTHEW A</creatorcontrib><creatorcontrib>NAGARAJ, BHARATH, H</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MOGLER MATTHEW A</au><au>NAGARAJ, BHARATH, H</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Swine influenza A virus vaccine comprising two different RNA replicon particles</title><date>2023-02-03</date><risdate>2023</risdate><abstract>The present invention relates to an immunogenic composition comprising first and second RNA replicon particles. The first RNA replicon particle comprises a nucleic acid construct comprising first and second nucleic acid sequences encoding first and second hemagglutinin (HA) antigens of swine influenza A virus (IAV-S). In some embodiments, the first HA antigen is an HA antigen of the A/swing/Gent/1/1984-like H3N2 (Gent/84) lineage, and the second HA antigen is an HA antigen of the A (H1N1) pdm09 (pdm09) lineage. The second RNA replicon particle comprises a nucleic acid construct comprising third and fourth nucleic acid sequences encoding third and fourth HA antigens of IAV-S. The third HA antigen is the HA antigen of the A/swing/Scotland/410440/1994-like H1huN2 (Scot/94) lineage, and the fourth HA antigen is the HA antigen of the Eurasian avian-like H1avN1 (EA) lineage. In other embodiments, the present invention relates to vaccines useful against influenza A virus infection and comprising an immunogenic compo</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng |
| recordid | cdi_epo_espacenet_CN115697398A |
| source | esp@cenet |
| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Swine influenza A virus vaccine comprising two different RNA replicon particles |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T07%3A51%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=MOGLER%20MATTHEW%20A&rft.date=2023-02-03&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN115697398A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |