Method for identifying crystal forms of low-content active ingredients in urea preparation

The invention relates to the technical field of medicament analysis, and particularly discloses a method for identifying crystal forms of low-content active ingredients in a urea preparation, which comprises the following steps of: respectively positioning concentrated distribution areas of the acti...

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Bibliographische Detailangaben
Hauptverfasser: GUAN DONG, ZHENG WANG, HE DELONG, WEI CUIWEN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to the technical field of medicament analysis, and particularly discloses a method for identifying crystal forms of low-content active ingredients in a urea preparation, which comprises the following steps of: respectively positioning concentrated distribution areas of the active ingredients and auxiliary materials by adopting a Raman imaging method; adopting a Raman imaging method to carry out multiple single-point detection on the active ingredient concentrated distribution area, and collecting the active ingredients; a Raman imaging method is adopted to carry out multiple single-point detection on the auxiliary material concentrated distribution area, and Raman signals of the auxiliary materials are collected; and deducting the Raman signal of the auxiliary material to optimize the characteristic peak signal of the active component in the preparation. According to the identification method, the positions of the active ingredients in the preparation are firstly positioned, then Raman s