Pyridone-containing condensed ring derivative inhibitor, and preparation method and application thereof

The invention discloses a pyridone-containing condensed ring derivative inhibitor as well as a preparation method and application thereof. Relates to a compound shown in a general formula (I) or a stereoisomer thereof, a preparation method thereof, a pharmaceutical composition containing the compoun...

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Hauptverfasser: LIU SHIQIANG, YUAN YIDA, HUANG SHENG'AI, BAO RUDI
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a pyridone-containing condensed ring derivative inhibitor as well as a preparation method and application thereof. Relates to a compound shown in a general formula (I) or a stereoisomer thereof, a preparation method thereof, a pharmaceutical composition containing the compound, and application of the compound as a Cap-dependent endonuclease inhibitor in treatment and/or prevention of related diseases caused by influenza viruses. 一种含吡啶酮稠环类衍生物抑制剂、其制备方法和应用。涉及通式(I)所示的化合物或其立体异构体、其制备方法及含有该化合物的药物组合物,及其作为Cap依赖的核酸内切酶抑制剂在治疗和/或预防由流感病毒引起的相关疾病中的应用。