Near-infrared emission fluorescent small molecule probe and preparation method thereof

The invention relates to a near-infrared emission fluorescent small molecular probe and a preparation method thereof, the near-infrared emission fluorescent small molecular probe is prepared through condensation reaction by taking BODIPY as a main light-emitting unit and an azo group as a specific r...

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Bibliographische Detailangaben
Hauptverfasser: GUO SHUANGHUA, WEN ZAICHENG, SUNG HWAN-IN, HUANG FEI, WU TAO, MA ZHENXIONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a near-infrared emission fluorescent small molecular probe and a preparation method thereof, the near-infrared emission fluorescent small molecular probe is prepared through condensation reaction by taking BODIPY as a main light-emitting unit and an azo group as a specific recognition group, and has the following structural formula: BODIPY-azobenzene derivatives with novel structures are constructed, and the near-infrared emission fluorescent small molecular probe is prepared by taking the BODIPY as the main light-emitting unit and taking the azo group as the specific recognition group. The series of molecules all take a hypoxic enzyme or azo specific recognition object as a target, the absorption and emission wavelengths of the prepared material are in a near-infrared first region range, the spectrum recognition range of a conventional hypoxic enzyme probe is exceeded, the application of the material is pushed forward by one step, and the material designed in the scheme is relatively