Preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factor
The invention discloses a preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factors, which comprises the following steps: adding glycerol into freeze-dried powder, and mixing/stirring until all powder particles are uniformly mixed with glycerol to form dou...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SHI JUNFANG XIE YUYI TENG LING YAO XIAOLIN |
| description | The invention discloses a preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factors, which comprises the following steps: adding glycerol into freeze-dried powder, and mixing/stirring until all powder particles are uniformly mixed with glycerol to form dough-shaped paste; then propylene glycol is added to the paste, and mixing/stirring is carried out, so that the final flowable paste is formed; the anhydrous ointment well solves the problems that stability cannot be maintained for a long time in an aqueous solution or hydrogel and inactivation is prone to occurring, in addition, a solution is used on a wound surface and is not prone to being preserved for a long time, and the use frequency is increased, use and storage are convenient, compared with a solution, the ointment can stay on the wound surface for a longer time, and the effect is good. The treatment effect is improved.
本发明公开了含重组人碱性成纤维细胞生长因子无水膏剂制备方法，包括以下步骤：将甘油添加到冻干粉中，并且混合/搅拌直到所有粉末颗粒都与甘油混合均匀，形成面团状糊剂；然后将丙二醇添加到 |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN115607506A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN115607506A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN115607506A3</originalsourceid><addsrcrecordid>eNqNyrEKwjAQgOEuDqK-w_kAQou0zlIUJ3FwL5f00gSau5BcEd9eBx_A6YePf12Nj0wJM2oQhkjqZQRxgOzfY5algATWSKxghRUDB54gk5VoAuOX_RKRwWAJFlwwWcyMRWHK8lIPDq1K3lYrh3Oh3a-ban-9PPvbgZIMVBJaYtKhvzdN29Wntu7Ox3-eD3u_P-g</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factor</title><source>esp@cenet</source><creator>SHI JUNFANG ; XIE YUYI ; TENG LING ; YAO XIAOLIN</creator><creatorcontrib>SHI JUNFANG ; XIE YUYI ; TENG LING ; YAO XIAOLIN</creatorcontrib><description>The invention discloses a preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factors, which comprises the following steps: adding glycerol into freeze-dried powder, and mixing/stirring until all powder particles are uniformly mixed with glycerol to form dough-shaped paste; then propylene glycol is added to the paste, and mixing/stirring is carried out, so that the final flowable paste is formed; the anhydrous ointment well solves the problems that stability cannot be maintained for a long time in an aqueous solution or hydrogel and inactivation is prone to occurring, in addition, a solution is used on a wound surface and is not prone to being preserved for a long time, and the use frequency is increased, use and storage are convenient, compared with a solution, the ointment can stay on the wound surface for a longer time, and the effect is good. The treatment effect is improved.
本发明公开了含重组人碱性成纤维细胞生长因子无水膏剂制备方法，包括以下步骤：将甘油添加到冻干粉中，并且混合/搅拌直到所有粉末颗粒都与甘油混合均匀，形成面团状糊剂；然后将丙二醇添加到</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230117&DB=EPODOC&CC=CN&NR=115607506A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230117&DB=EPODOC&CC=CN&NR=115607506A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHI JUNFANG</creatorcontrib><creatorcontrib>XIE YUYI</creatorcontrib><creatorcontrib>TENG LING</creatorcontrib><creatorcontrib>YAO XIAOLIN</creatorcontrib><title>Preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factor</title><description>The invention discloses a preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factors, which comprises the following steps: adding glycerol into freeze-dried powder, and mixing/stirring until all powder particles are uniformly mixed with glycerol to form dough-shaped paste; then propylene glycol is added to the paste, and mixing/stirring is carried out, so that the final flowable paste is formed; the anhydrous ointment well solves the problems that stability cannot be maintained for a long time in an aqueous solution or hydrogel and inactivation is prone to occurring, in addition, a solution is used on a wound surface and is not prone to being preserved for a long time, and the use frequency is increased, use and storage are convenient, compared with a solution, the ointment can stay on the wound surface for a longer time, and the effect is good. The treatment effect is improved.
本发明公开了含重组人碱性成纤维细胞生长因子无水膏剂制备方法，包括以下步骤：将甘油添加到冻干粉中，并且混合/搅拌直到所有粉末颗粒都与甘油混合均匀，形成面团状糊剂；然后将丙二醇添加到</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQgOEuDqK-w_kAQou0zlIUJ3FwL5f00gSau5BcEd9eBx_A6YePf12Nj0wJM2oQhkjqZQRxgOzfY5algATWSKxghRUDB54gk5VoAuOX_RKRwWAJFlwwWcyMRWHK8lIPDq1K3lYrh3Oh3a-ban-9PPvbgZIMVBJaYtKhvzdN29Wntu7Ox3-eD3u_P-g</recordid><startdate>20230117</startdate><enddate>20230117</enddate><creator>SHI JUNFANG</creator><creator>XIE YUYI</creator><creator>TENG LING</creator><creator>YAO XIAOLIN</creator><scope>EVB</scope></search><sort><creationdate>20230117</creationdate><title>Preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factor</title><author>SHI JUNFANG ; XIE YUYI ; TENG LING ; YAO XIAOLIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115607506A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SHI JUNFANG</creatorcontrib><creatorcontrib>XIE YUYI</creatorcontrib><creatorcontrib>TENG LING</creatorcontrib><creatorcontrib>YAO XIAOLIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHI JUNFANG</au><au>XIE YUYI</au><au>TENG LING</au><au>YAO XIAOLIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factor</title><date>2023-01-17</date><risdate>2023</risdate><abstract>The invention discloses a preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factors, which comprises the following steps: adding glycerol into freeze-dried powder, and mixing/stirring until all powder particles are uniformly mixed with glycerol to form dough-shaped paste; then propylene glycol is added to the paste, and mixing/stirring is carried out, so that the final flowable paste is formed; the anhydrous ointment well solves the problems that stability cannot be maintained for a long time in an aqueous solution or hydrogel and inactivation is prone to occurring, in addition, a solution is used on a wound surface and is not prone to being preserved for a long time, and the use frequency is increased, use and storage are convenient, compared with a solution, the ointment can stay on the wound surface for a longer time, and the effect is good. The treatment effect is improved.
本发明公开了含重组人碱性成纤维细胞生长因子无水膏剂制备方法，包括以下步骤：将甘油添加到冻干粉中，并且混合/搅拌直到所有粉末颗粒都与甘油混合均匀，形成面团状糊剂；然后将丙二醇添加到</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng |
| recordid | cdi_epo_espacenet_CN115607506A |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factor |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T22%3A12%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SHI%20JUNFANG&rft.date=2023-01-17&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN115607506A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |