Preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factor

The invention discloses a preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factors, which comprises the following steps: adding glycerol into freeze-dried powder, and mixing/stirring until all powder particles are uniformly mixed with glycerol to form dou...

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Bibliographische Detailangaben
Hauptverfasser: SHI JUNFANG, XIE YUYI, TENG LING, YAO XIAOLIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a preparation method of anhydrous ointment containing recombinant human basic fibroblast growth factors, which comprises the following steps: adding glycerol into freeze-dried powder, and mixing/stirring until all powder particles are uniformly mixed with glycerol to form dough-shaped paste; then propylene glycol is added to the paste, and mixing/stirring is carried out, so that the final flowable paste is formed; the anhydrous ointment well solves the problems that stability cannot be maintained for a long time in an aqueous solution or hydrogel and inactivation is prone to occurring, in addition, a solution is used on a wound surface and is not prone to being preserved for a long time, and the use frequency is increased, use and storage are convenient, compared with a solution, the ointment can stay on the wound surface for a longer time, and the effect is good. The treatment effect is improved. 本发明公开了含重组人碱性成纤维细胞生长因子无水膏剂制备方法,包括以下步骤:将甘油添加到冻干粉中,并且混合/搅拌直到所有粉末颗粒都与甘油混合均匀,形成面团状糊剂;然后将丙二醇添加到