Illicium henryi liposome, preparation method and gel ointment thereof

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to illicium henryi liposome and a gel ointment thereof. The illicium henryi liposome is prepared from an illicium henryi extract, phospholipid, a sterol compound and disodium succinate...

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Hauptverfasser: LI YONGLIANG, ZHENG YING, ZOU JIE, XU AIQIN, LIU WEIYE, CHEN PINYU, HE WEIKANG, ZHOU LIMIN, QI ZHIMIN, YANG JIANFENG, WANG WENXI, DAI ANYIN, WANG YIN, YU TINGTING, FANG HUI, ZHENG SHANJIAO, CHEN NUOHAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to illicium henryi liposome and a gel ointment thereof. The illicium henryi liposome is prepared from an illicium henryi extract, phospholipid, a sterol compound and disodium succinate. The lipidosome is used as a carrier of the active component of the illicium henryi, and the formula ratio is optimized, so that the encapsulation efficiency of the illicium henryi lipidosome is improved, the leakage rate is reduced, the particle size is uniform, and the stability is obviously improved. According to the gel ointment provided by the invention, the transdermal efficiency of the active ingredient quercitrin is improved, and the gel ointment is more beneficial to continuously exerting a good treatment effect on skin and deep tissues thereof. 本发明属于中药制剂技术领域,具体涉及一种红茴香脂质体及其凝胶膏剂。本发明红茴香脂质体包括红茴香提取物、磷脂、甾醇类化合物、琥珀酸二钠。采用脂质体作为红茴香活性成分的载体,优选配方配比,提高了红茴香脂质体的包封率,降低了渗漏率,使其粒径均一、稳定性显著提升。本发明提供的凝胶膏剂提高了活性成分槲皮苷的透皮效率,更有利于其在皮肤