Method and tool for estimating sex karyotype, computer device, and storage medium

The invention is suitable for the field of biological information, and provides a sex chromosome karyotype speculation method and tool, computer equipment and a storage medium, the method comprises the following steps: obtaining file information of a to-be-detected sample, the file information comprising gene sequencing information; extracting a plurality of gender-related features from the file information of the to-be-tested sample, and incorporating the gender-related features into a preset Gaussian mixture model; carrying out sample clustering on the incorporated features through the Gaussian mixture model; and speculating the sex chromosome karyotype of the to-be-detected sample according to a sample clustering result. According to the embodiment of the invention, the unsupervised learning-Gaussian mixture model is used for deducing the sequencing sample karyotype, and for data with different covariance structures, the speculation performance and accuracy are higher, and the universality is realized. 本发明