Beta-9 glutamic acid, beta-10 aspartic acid| human insulin

A B9G/u, B10Asp¦ human insulin obtained by protein engineering technology features that the 9th and 10th positions in B chain all are acidic amino acids, the bind power of its acceptor is 34.4% thatof pig's insulin and its bioactivity in body is basically the same as natural insulin. It is desi...

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Bibliographische Detailangaben
Hauptverfasser:	YUEHUA TANG, ZHENHE LIANG, YOUMIN FENG
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES SPIRITS VINEGAR WINE
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Zusammenfassung:	A B9G/u, B10Asp¦ human insulin obtained by protein engineering technology features that the 9th and 10th positions in B chain all are acidic amino acids, the bind power of its acceptor is 34.4% thatof pig's insulin and its bioactivity in body is basically the same as natural insulin. It is desirable to use it as quick-acting insulin monomer in clinical application. A £B9G/u, B10Asp\| human insulin obtained by protein engineering technology features that the 9th and 10th positions in B chain all are acidic amino acids, the bind power of its acceptor is 34.4% thatof pig's insulin and its bioactivity in body is basically the same as natural insulin. It is desirable to use it as quick-acting insulin monomer in clinical application.