Biopolymer sequencing method
The present disclosure provides devices, systems, and methods related to biopolymer sequencing. In particular, the present disclosure relates to methods of sequencing polynucleotides using a bioelectronic device that obtains a bioelectronic signature (e.g., current amplitude level) of polymerase act...
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| creator | LYNDERSAY SEAN |
| description | The present disclosure provides devices, systems, and methods related to biopolymer sequencing. In particular, the present disclosure relates to methods of sequencing polynucleotides using a bioelectronic device that obtains a bioelectronic signature (e.g., current amplitude level) of polymerase activity based on current fluctuations when complementary nucleotide polyphosphate monomers (e.g., with a unique charge) are incorporated into a template polynucleotide.
本公开提供了与生物聚合物测序相关的装置、系统和方法。具体而言，本公开涉及使用生物电子装置对多核苷酸进行测序的方法，所述生物电子装置基于当(例如具有独特电荷的)互补核苷酸多磷酸单体被掺入到模板多核苷酸中时的电流波动获得聚合酶活性的生物电子签名(例如电流幅度水平)。 |
| format | Patent |
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本公开提供了与生物聚合物测序相关的装置、系统和方法。具体而言，本公开涉及使用生物电子装置对多核苷酸进行测序的方法，所述生物电子装置基于当(例如具有独特电荷的)互补核苷酸多磷酸单体被掺入到模板多核苷酸中时的电流波动获得聚合酶活性的生物电子签名(例如电流幅度水平)。</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; DERIVATIVES THEREOF ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; SUGARS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221230&DB=EPODOC&CC=CN&NR=115552033A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25566,76549</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221230&DB=EPODOC&CC=CN&NR=115552033A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LYNDERSAY SEAN</creatorcontrib><title>Biopolymer sequencing method</title><description>The present disclosure provides devices, systems, and methods related to biopolymer sequencing. In particular, the present disclosure relates to methods of sequencing polynucleotides using a bioelectronic device that obtains a bioelectronic signature (e.g., current amplitude level) of polymerase activity based on current fluctuations when complementary nucleotide polyphosphate monomers (e.g., with a unique charge) are incorporated into a template polynucleotide.
本公开提供了与生物聚合物测序相关的装置、系统和方法。具体而言，本公开涉及使用生物电子装置对多核苷酸进行测序的方法，所述生物电子装置基于当(例如具有独特电荷的)互补核苷酸多磷酸单体被掺入到模板多核苷酸中时的电流波动获得聚合酶活性的生物电子签名(例如电流幅度水平)。</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>DERIVATIVES THEREOF</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PHYSICS</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>SUGARS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJBxyswvyM-pzE0tUihOLSxNzUvOzEtXyE0tychP4WFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8c5-hoampqZGBsbGjsbEqAEAw6kkCg</recordid><startdate>20221230</startdate><enddate>20221230</enddate><creator>LYNDERSAY SEAN</creator><scope>EVB</scope></search><sort><creationdate>20221230</creationdate><title>Biopolymer sequencing method</title><author>LYNDERSAY SEAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115552033A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>DERIVATIVES THEREOF</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PHYSICS</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>SUGARS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>LYNDERSAY SEAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LYNDERSAY SEAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Biopolymer sequencing method</title><date>2022-12-30</date><risdate>2022</risdate><abstract>The present disclosure provides devices, systems, and methods related to biopolymer sequencing. In particular, the present disclosure relates to methods of sequencing polynucleotides using a bioelectronic device that obtains a bioelectronic signature (e.g., current amplitude level) of polymerase activity based on current fluctuations when complementary nucleotide polyphosphate monomers (e.g., with a unique charge) are incorporated into a template polynucleotide.
本公开提供了与生物聚合物测序相关的装置、系统和方法。具体而言，本公开涉及使用生物电子装置对多核苷酸进行测序的方法，所述生物电子装置基于当(例如具有独特电荷的)互补核苷酸多磷酸单体被掺入到模板多核苷酸中时的电流波动获得聚合酶活性的生物电子签名(例如电流幅度水平)。</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES DERIVATIVES THEREOF ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS SUGARS TESTING VINEGAR WINE |
| title | Biopolymer sequencing method |
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