Antigen binding proteins targeting GPC3

The invention relates to a separated antigen binding protein, which comprises the separated antigen binding protein, the separated antigen binding protein comprises at least one CDR in an antibody heavy chain variable region VH, and the VH comprises an amino acid sequence as shown in SEQ ID NO: 17....

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Bibliographische Detailangaben
Hauptverfasser:	JIANG YUCHAO, MIAO JIA, SUN NAICHAO, ZHOU MAODE, LIU HENG, WANG MIAOMIAO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a separated antigen binding protein, which comprises the separated antigen binding protein, the separated antigen binding protein comprises at least one CDR in an antibody heavy chain variable region VH, and the VH comprises an amino acid sequence as shown in SEQ ID NO: 17. The separated antigen binding protein disclosed by the invention can be specifically bound with GPC3. The invention also provides a preparation method and application of the antigen binding protein. 本申请涉及一种分离的抗原结合蛋白，其包含分离的抗原结合蛋白，所述分离的抗原结合蛋白包含抗体重链可变区VH中的至少一个CDR，所述VH包含SEQ ID NO:17所示的氨基酸序列。本申请所述的分离的抗原结合蛋白能够特异性结合GPC3。本申请还提供了所述抗原结合蛋白的制备方法及用途。