Preparation method and application of phosphino compound

The invention discloses a preparation method and application of a phosphino compound, and belongs to the technical field of organic synthesis. The method comprises the following steps: 1, mixing a phosphine oxide compound R3PO with a proton compound in an inert gas or nitrogen atmosphere to obtain a mixture; the method comprises the following steps: 1, preparing a mixture, 2, adding metal sodium, a phosphine oxide compound R3PO, a proton compound and the metal sodium into the mixture obtained in the first step, and carrying out a full reaction to generate NaOH or a proton compound sodium salt, R2PONa and an R-series organic matter, and 3, after the reaction is finished, separating the NaOH or proton compound sodium salt, R2PONa and the R-series organic matter generated by the reaction to obtain R2PONa. The preparation method can make up various defects caused by the preparation method of R1R2PONa prepared by using R3PO to react with sodium in the prior art. 本发明公开了一种膦基化合物的制备方法及其应用，属于有机合成技术领域。它包括如下步骤：第一步：在惰性气体或