Application of PI3K inhibitor in preparation of medicine for treating or preventing respiratory system inflammatory diseases

The invention discloses application of 1, 3-dimethyl-1, 3-dihydro-2H-cyclopentadiene [gh] piperidine-2-ketone in preparation of a medicine for treating or preventing respiratory system inflammatory diseases, and the 1, 3-dimethyl-1, 3-dihydro-2H-cyclopentadiene [gh] piperidine-2-ketone is used for preventing and/or relieving and/or assisting in treating and/or treating the respiratory system inflammatory diseases. Such as asthma, pneumonia, tracheitis, bronchitis, pulmonary interstitial fibrosis or chronic obstructive pulmonary disease. The 1, 3-dimethyl-1, 3-dihydro-2H-cyclopentadiene [gh] piperidine-2-ketone disclosed by the invention has a specific inhibition effect on PI3K gamma and has an inhibition effect on chemotaxis of inflammatory cells and release of inflammatory factors, and the compound disclosed by the invention can be used for inhibiting inflammatory reaction by inhibiting PI3K. 本发明公开了1,3-二甲基-1,3-二氢-2H-环戊二烯[gh]哌啶-2-酮在制备治疗或预防呼吸系统炎症性疾病药物中的应用，用于预防和/或缓解和/或辅助治疗和/或治疗呼吸系统炎症性疾病，如哮喘、肺炎、气管炎、支气管炎、肺间质纤维化或慢