Preparation method of doxycycline hydrochloride granules
The invention relates to the technical field of veterinary drugs, in particular to a preparation method of doxycycline hydrochloride granules, which comprises the following steps: (1) taking sodium carboxymethyl starch, adopting purified water as a solvent, and preparing a sodium carboxymethyl starc...
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| creator | FU CHENGLI YANG AOYU WANG ZHAOPING |
| description | The invention relates to the technical field of veterinary drugs, in particular to a preparation method of doxycycline hydrochloride granules, which comprises the following steps: (1) taking sodium carboxymethyl starch, adopting purified water as a solvent, and preparing a sodium carboxymethyl starch solution with the mass concentration of 5-15% as an adhesive; (2) respectively sieving doxycycline hydrochloride raw powder, anhydrous dextrose and cationic polyacrylamide with the molecular weight of 12 million, and collecting for later use; (3) the adhesive in the step (1) and the raw materials sieved in the step (2) are sequentially put into a fluidized bed for granulation, and cationic polyacrylamide and anhydrous dextrose are added according to the mass ratio of the cationic polyacrylamide to the doxycycline hydrochloride raw powder being (1.5-3): 5 and the mass ratio of the anhydrous dextrose to the doxycycline hydrochloride raw powder being (2-4): 5; in the granulation process, the air inlet temperature is |
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| language | chi ; eng |
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| subjects | BABY COMFORTERS CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY DEVICES FOR RECEIVING SPITTLE DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Preparation method of doxycycline hydrochloride granules |
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